Anti-Human CD273 APC (Clone : 24F.10C12)
Product Sizes
100 tests
£620.00
30-2602-100TESTS
About this Product
- SKU:
- 30-2602
- Additional Names:
- PDCD1LG2; B7DC; Btdc; PDL2; PDCD1L2; bA574F11.2; Butyrophilin; B7-DC;programmed cell death 1 ligand 2
- translate.label.attr.clone:
- 24F.10C12
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD273 / PD-L2 (programmed death ligand-1); also known as B7-DC; is a member of the B7 family of regulatory proteins. It costimulates the proliferation of T cells; and mediates IFN gamma production. Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses. When interacting with CD279; it can act as a coinhibitor of the T cell function. CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.Specificity : The mouse monoclonal antibody 24F.10C12 recognizes an extracellular epitope of CD273 / PD-L2 (also known as B7-DC); a 25 kDa type I transmembrane protein expressed by dendritic cells; activated monocytes and T cells; heart; first trimester placenta; lung and liver; as well as in Hodgkin´s lymphoma cells and primary mediastinal B cell lymphoma (PMBL).
- Immunogen:
- human CD273
- Isotype:
- Mouse IgG2a kappa
- Purification:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
