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Antibodies

Anti-Human CD279 FITC (Clone : EH12.2H7)

Product Sizes
100 tests
£581.00
30-2599-100TESTS
About this Product
SKU:
30-2599
Additional Names:
PDCD1; PD1; SLEB2;programmed cell death 1
translate.label.attr.clone:
EH12.2H7
Clonality:
Monoclonal
Conjugate:
FITC
Extra Details:
CD279 / PD-1 (programmed cell death 1); a transmembrane protein of CD28/CTLA-4 family. It is expressed inducibly mainly on activated T; B; and myeloid cells and plays a role in maintaining peripheral self-tolerance. Binding to its receptors CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their anergy. It is also expressed during thymic development. Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus; type 1 diabetes; and rheumatoid arthritis.Specificity : The mouse monoclonal antibody EH12.2H7 recognizes an extracellular epitope of CD279 / PD-1 (programmed cell death 1); a 55 kDa type I transmembrane protein expressed above all during T cell development; on activated T cells; activated B cells; and activated monocytes.
Isotype:
Mouse IgG1 kappa
Purification:
The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2 : Separation of human CD297 positive cells (red-filled) from cellular debris (black-dashed) in flow cytometry analysis (surface staining) of human PHA stimulated peripheral blood mononuclear cells stained using anti-human CD279 (EH12.2H7) FITC antibody (4 µl reagent per milion cells in 100 µl of cell suspension).
Figure 2 : Separation of human CD297 positive cells (red-filled) from cellular debris (black-dashed) in flow cytometry analysis (surface staining) of human PHA stimulated peripheral blood mononuclear cells stained using anti-human CD279 (EH12.2H7) FITC antibody (4 µl reagent per milion cells in 100 µl of cell suspension).