Anti-Human CD35 APC (Clone : E11)
Product Sizes
100 tests
£620.00
30-2576-100TESTS
About this Product
- SKU:
- 30-2576
- Additional Names:
- CR1; KN; C3BR; C4BR;complement C3b/C4b receptor 1 (Knops blood group)
- translate.label.attr.clone:
- E11
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD35 (complement receptor 1; CR1) is a monomeric multiple modular cell surface glycoprotein which serves as receptor for C3b and C4b; the most important components of the complement system leading to clearance of foreign macromolecules. It is expressed mainly on the surface of granulocytes; monocytes; erythrocytes; B cells and folicular dendritic cells. Besides its role in complement cascade; CD35 is involved in blocking BCR-induced proliferation and the differentiation of B cells to plasmablasts and their Ig production.Specificity : The mouse monoclonal antibody E11 recognizes an extracellular epitope of CD35 (CR1); a type I transmembrane glycoprotein expressed on granulocytes; monocytes; B cells; folicular dendritic cells; erythrocytes; NK and T cell subsets; as well as e.g. on glomerulal podocytes.
- Immunogen:
- Acute monocytic leukemia cells and normal blood monocytes
- Isotype:
- Mouse IgG1
- Purification:
- The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
