Anti-Human CD41/CD61 (PAC-1 epitope) PE (Clone : PAC-1)
Product Sizes
100 tests
£620.00
30-2566-100TESTS
About this Product
- SKU:
- 30-2566
- Additional Names:
- platelet GPIIb; Integrin alpha-Iib; GPalpha IIb; GPIIb; GT; GP3A; platelet GPIIIa
- translate.label.attr.clone:
- PAC-1
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD41 (platelet glycoprotein IIb; integrin alpha IIb) is composed of two subunits (120 kDa transmembrane alpha chain and 23 kDa extracellular beta chain) and interacts with CD61 (platelet glycoprotein IIIa; integrin beta 3) in the presence of calcium to form a functional adhesive protein receptor. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. Upon blood vessel damage; this receptor binds to a variety of proteins including von Willebrand factor; fibrinogen; fibronectin and vitronectin; and it is involved in platelet aggregation.Specificity : The mouse monoclonal antibody PAC-1 recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa); also known as integrin alpha IIb beta 3; a receptor which mediates platelet aggregation.
- Immunogen:
- Human platelets
- Isotype:
- Mouse IgM kappa
- Purification:
- The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
