Anti-Mouse CD49e Azide Free Antibody (Clone : 5H10-27 (MFR5))
Product Sizes
0.1 mg
£482.00
30-2556-0.1MG
About this Product
- SKU:
- 30-2556
- Additional Names:
- ITGA5; VLA-5 alpha; FNRA;integrin alpha 5
- translate.label.attr.clone:
- 5H10-27 (MFR5)
- Clonality:
- Monoclonal
- Extra Details:
- CD49e; the alpha 5 integrin; noncovalently associates with the beta 1integrin (CD29) to form VLA-5 integrin complex. CD49e itself is composed of two disulfide-linked chains of 135 kDa and 25 kDa. VLA-5 binds to RGD sequence of fibronectin; and to neural adhesion molecule L1. It is important in maintaining the integrity of endothelial monolayers; in monocyte migration into the extracellular tissues; and it also provides a co-stimulatory signal to T cells and enhances receptor and complement receptor-mediated phagocytosis. Specificity : The rat monoclonal antibody 5H10-27 (MFR5) recognizes an extracellular epitope of murine CD49e; a 135 kDa protein serving as VLA-5 alpha chain; expressed on thymocytes; activated T cells; splenic B cells; and mast cells.
- Format:
- Azide Free
- Immunogen:
- C57BL/6 x A/J)F1 murine mast cell line
- Isotype:
- Rat IgG2a kappa
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:30-2556.jpeg
