Anti-Human CD51/CD61 Antibody (Clone : 23C6)
Product Sizes
0.1 mg
£541.00
30-2554-0.1MG
About this Product
- SKU:
- 30-2554
- Additional Names:
- VNRA; MSK8; ITGB3; ITGAV; Integrin alpha5beta3; OFA; VR
- translate.label.attr.clone:
- 23C6
- Clonality:
- Monoclonal
- Extra Details:
- CD51/CD61 (integrin alpha5beta3); also known as osteoclast functional antigen; serves as a vitronectin receptor; and binds also to fibronectin; fibrinogen; thrombospondin; osteopontin; collagen; and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts; placenta; and endothelial cells; at lower levels on platelets and macrophages.Specificity : The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex; that is expressed mainly on human osteoclasts; but also e.g. on placenta; or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
- Format:
- Purified
- Immunogen:
- A cell suspension containing osteoclasts from osteoclastomas
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:1.jpg
