Anti-HDAC6 Antibody (Clone : 2H3)
Product Sizes
0.1 mg
£541.00
30-2523-0.1MG
About this Product
- SKU:
- 30-2523
- Additional Names:
- Histone deacetylase 6;histone deacetylase 6
- translate.label.attr.clone:
- 2H3
- Clonality:
- Monoclonal
- Extra Details:
- Histone deacetylase 6 (HDAC6); like other histone deacetylases; affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones; HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha; and is involved in protein trafficking and degradation; as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.Specificity : The mouse monoclonal antibody 2H3 recognizes D1 domain of human histone deacetylase 6 (HDAC6; intracellular antigen); amino acids 281-291. Crossreactivity with other species was not tested.
- Format:
- Purified
- Immunogen:
- human HDAC6
- Isotype:
- Mouse IgG1 kappa
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:download_pdf.php
