Anti-HLA-E Antibody (Clone : 3D12)
Product Sizes
0.1 mg
£570.00
30-2520-0.1MG
About this Product
- SKU:
- 30-2520
- Additional Names:
- HLA class I histocompatibility antigen; alpha chain E; MHC class I antigen E;major histocompatibility complex; class I; E
- translate.label.attr.clone:
- 3D12
- Clonality:
- Monoclonal
- Extra Details:
- HLA-E (Human Leukocyte Antigen E) is a non-classical MHC I antigen; which is important for dialogue with NK cells and their regulation through interaction with CD94/NKG2 receptor. Like other MHC I molecules; transmembrane HLA-E molecule (45 kDa) associates with beta2 microglobulin. Unlike HLA-G; expression of HLA-E molecules is not so restricted; but it has been detected at least at mRNA level in virtually all cells and tissues examined. In peripheral blood; HLA-E protein is expressed at least in all mononuclear cells; but in different quantity (B cells and monocytes more than T cells and NK cells).Specificity : The mouse monoclonal antibody 3D12 (also known as 3D12HLA-E) recognizes native extracellular part of HLA-E; an ubiquitously expressed non-classical MHC class I molecule; as well as free HLA-E.
- Format:
- Purified
- Isotype:
- Mouse IgG1
- Purification:
- Purified from cell culture supernatant by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:1.jpg
