Anti-Mouse LPAM-1 PE (Clone : DATK32)
Product Sizes
0.1 mg
£541.00
30-2511-0.1MG
About this Product
- SKU:
- 30-2511
- Additional Names:
- Integrin alpha 4 beta 7; CD49d / Ly69
- translate.label.attr.clone:
- DATK32
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- Integrin alpha 4 / beta 7 (CD49d / Ly69) ; also known as LPAM-1 (Lymphocyte Peyer´s patch adhesion molecule 1); is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria. It is expressed primarily on mucosal lymphocytes; but is also present on NK cells and eosinophils. Ligands of LPAM-1 are MAdCAM-1; VCAM-1; and fibronectin; but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.Specificity : The rat monoclonal antibody DATK32 recognizes an extracellular epitope of integrin alpha 4 (CD49d) and integrin beta7 (Ly69) components of mouse LPAM-1 complex; which is expressed on the majority of peripheral lymphocytes; as well as on subsets of thymocytes and bone marrow cells.
- Immunogen:
- TK1 cells
- Isotype:
- Rat IgG2a kappa
- Purification:
- The purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
