Anti-p21Waf1 Antibody (Clone : WA-1)
Product Sizes
0.1 mg
£551.00
30-2498-0.1MG
About this Product
- SKU:
- 30-2498
- Additional Names:
- CDKN1A; CIP1; CAP20;cyclin dependent kinase inhibitor 1A
- translate.label.attr.clone:
- WA-1
- Clonality:
- Monoclonal
- Extra Details:
- The tumour suppressor p21Waf1 (Wild-type p53-Activated Fragment 1; also known as Cip1; Cdk interacting protein; or SDI 1) is a cyclin-dependent kinase (Cdk) inhibitor; which is expressed by involvement of p53; Egr-1; AP2; STATs or other transcription factors upon various stimuli resulting in cell cycle arrest. Through its N-terminal domain p21Waf1 inhibits Cdk activity; whereas through the C-terminal domain it inhibits the activity of PCNA (proliferating cell nuclear antigen) to activate DNA replication. Cytosolic location of p21 counteracts its inhibitory activities.Specificity : The antibody WA-1 reacts with p21 protein (Waf1; Cip1; SDI 1; intracellular antigen); a 21 kDa tumour suppressor; which inhibits the activity of cyclin-dependent family kinases and of proliferating cell nuclear antigen.
- Format:
- Purified
- Immunogen:
- Human p21 protein
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:1.jpg
