Anti-Human SIGLEC8 Antibody (Clone : 7C9)
Product Sizes
0.1 mg
£541.00
30-2496-0.1MG
About this Product
- SKU:
- 30-2496
- Additional Names:
- SAF2;sialic acid binding Ig like lectin 8
- translate.label.attr.clone:
- 7C9
- Clonality:
- Monoclonal
- Extra Details:
- SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM); and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker; although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum; especially in case of eosinophil-associated diseases.Specificity : The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8; an eosinophil marker; expressed e.g. in lymph nodes and spleen.
- Format:
- Purified
- Immunogen:
- Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies
- Manufacturer's Data Sheet:1.jpg
