Anti-CD33 Monoclonal Antibody (Clone:WM53)-PerCP Conjugated
Product Sizes
100 tests
£620.00
30-2451-100TESTS
About this Product
- SKU:
- 30-2451
- Additional Names:
- CD33||SIGLEC3
- translate.label.attr.clone:
- WM53
- Clonality:
- Monoclonal
- Conjugate:
- PerCP
- Extra Details:
- CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage; binds sialic acid residues in N- and O-glycans on cell surfaces; and is a therapeutic target for acute myeloid leukemia.
- Host:
- Mouse
- Immunogen:
- Human AML cells
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
