PE Conjugated Anti-LARGE1 Monoclonal Antibody (Clone:LARGE-02)
Product Sizes
0.1 mg
£620.00
30-2346-0.1MG
About this Product
- SKU:
- 30-2346
- Additional Names:
- LARGE1||KIAA0609||LARGE
- translate.label.attr.clone:
- LARGE-02
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- LARGE1 serves as a glycosyltransferase which participates in glycosylation of the muscle membrane protein alpha-dystroglycan. Mutations of LARGE1 lead to hypoglycosylation of alpha-dystroglycan and cause congenital muscular dystrophy (MDC1D) associated with severe mental retardation. Altered alpha-dystroglycan glycosylation may also play a role in cancer; as hypoglycosylation of the protein and loss of laminin binding have been demonstrated in invasive carcinoma cells.
- Host:
- Mouse
- Immunogen:
- Recombinant fragment of human LARGE1 (amino acids 35-142)
- Isotype:
- Mouse IgG2b
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
