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Antibodies

Anti-CD11b Monoclonal Antibody (Clone:ICRF44)-PE Conjugated

Product Sizes
100 tests
£620.00
30-2332-100TESTS
About this Product
SKU:
30-2332
Additional Names:
ITGAM||CD11B||CR3A
translate.label.attr.clone:
ICRF44
Clonality:
Monoclonal
Conjugate:
PE
Extra Details:
CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1; CR3) is highly expressed on NK cells; neutrophils; monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes; macrophages and granulocytes; facilitating their diapedesis; as well as it mediates the uptake of complement coated particles; serving as a receptor for the iC3b fragment of the third complement component.
Host:
Mouse
Immunogen:
Rheumatoid synovial cells and human monocytes.
Isotype:
Mouse IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg