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Antibodies

Anti-CD158d / KIR2DL4 Monoclonal Antibody (Clone:mAb#33)-PE Conjugated

Product Sizes
100 tests
£620.00
30-2288-100TESTS
About this Product
SKU:
30-2288
Additional Names:
KIR2DL4||CD158D||KIR103AS
translate.label.attr.clone:
mAb#33
Clonality:
Monoclonal
Conjugate:
PE
Extra Details:
CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM; suggesting inhibitory function; but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells; but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
Host:
Mouse
Immunogen:
NK3.3 cells and KIR2DL4-Ig fusion protein
Isotype:
Mouse IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 1: Separation of cells stained using anti-human CD158d (mAb#33) PE antibody from cells stained using mouse IgG1 isotype control (MOPC-21) PE antibody in flow cytometry analysis (surface staining) of NKL cell suspension.