Anti-CD45R0 Monoclonal Antibody (Clone:UCHL1)-PE Conjugated
Product Sizes
100 tests
£620.00
30-2245-100TESTS
About this Product
- SKU:
- 30-2245
- translate.label.attr.clone:
- UCHL1
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD45R0 is the shortest isoform of a receptor-type protein tyrosine phosphatase; CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling; serving as an important regulator of Src-family kinases; promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains; whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45R0 is expressed e.g. on macrophages; CD8+ T cells; activated T cells and myeloma cells.
- Host:
- Mouse
- Immunogen:
- Human IL-2 dependent T cells
- Isotype:
- Mouse IgG2a
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
