Anti-CD95 / Fas Monoclonal Antibody (Clone:LT95)-PE Conjugated
Product Sizes
100 tests
£620.00
30-2215-100TESTS
About this Product
- SKU:
- 30-2215
- Additional Names:
- Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor
- translate.label.attr.clone:
- LT95
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD95 (Fas; APO-1); a 46 kDa transmembrane glycoprotein; is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains; formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC; in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis; Fas also triggers pro-inflammatory cytokine responses.
- Host:
- Mouse
- Immunogen:
- HUT-78 human T cell lymphoma cell line
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
