Anti-CD50 / ICAM-3 Monoclonal Antibody (Clone:MEM-171)-PE Conjugated
Product Sizes
100 tests
£620.00
30-2187-100TESTS
About this Product
- SKU:
- 30-2187
- Additional Names:
- ICAM3
- translate.label.attr.clone:
- MEM-171
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD50 (intracellular adhesion molecule 3; ICAM-3) is a transmembrane glycoprotein expressed by leukocytes; that serves as a counter-receptor for the lymphocyte function-associated antigen (LFA)-1 integrin. Besides functioning as an adhesive molecule that mediates e.g. the contact between T cells and antigen presenting cells; ICAM-3 regulates affinity of LFA-1 for ICAM-1 and induces T cell activation and proliferation. ICAM-3 plays an essential role in the initiation of the immune response both on T cells and antigen presenting cells and interacts also with CD209 (dendritic cell-specific ICAM-3-grabbing nonintegrin; DC-SIGN); a C-type lectin of dendritic cells and macrophages; this process is involved in dialogue between dendritic cells and granulocytes.
- Host:
- Mouse
- Immunogen:
- Human granulocytes
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
