Anti-CD22 Monoclonal Antibody (Clone:MEM-01)-PE Conjugated
Product Sizes
100 tests
£620.00
30-2186-100TESTS
About this Product
- SKU:
- 30-2186
- Additional Names:
- CD22||SIGLEC2
- translate.label.attr.clone:
- MEM-01
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD22; also known as Siglec-2 (sialic acid-binding immunoglobulin-like lectin-2) is a transmembrane glycoprotein binding alpha2;6-linked sialic acid-bearing ligands. Intracellular domain of CD22 recruits protein tyrosine phosphatase SHP-1 through the immunoreceptor tyrosine-based inhibitory motifs (ITIMs); thus setting a treshold for B cell receptor-mediated activation. CD22 also regulates B-cell response by involvement in controlling the CD19/CD21-Src-family protein tyrosine kinase amplification pathway and CD40 signaling. CD22 exhibits hallmarks of clathrin-mediated endocytic pathway.
- Host:
- Mouse
- Immunogen:
- Raji Burkitt's lymphoma cell line
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
