Anti-CD53 Monoclonal Antibody (Clone:MEM-53)-PE Conjugated
Product Sizes
100 tests
£620.00
30-2175-100TESTS
About this Product
- SKU:
- 30-2175
- Additional Names:
- CD53||MOX44||TSPAN25
- translate.label.attr.clone:
- MEM-53
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2; CD19; CD21; MHC II; VLA-4 or tetraspanins CD37; CD81 and CD82; thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus; CD53 is up-regulated in response to positive selection signals during T cell development; and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide; whereas stimulation of neutrophils results in down-regulation of CD53 expression.
- Host:
- Mouse
- Immunogen:
- Leukocytes of pacient suffering from a LGL-type leukemia.
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
