Anti-CD45RA Monoclonal Antibody (Clone:MEM-56)-PE Conjugated
Product Sizes
100 tests
£620.00
30-2172-100TESTS
About this Product
- SKU:
- 30-2172
- Additional Names:
- Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; CD45
- translate.label.attr.clone:
- MEM-56
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD45RA is a high molecular weight isoform of a receptor-type protein tyrosine phosphatase; CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling; serving as an important regulator of Src-family kinases; promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains; whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RA is expressed e.g. on naive T cells and normal plasma cells.
- Host:
- Mouse
- Immunogen:
- Human thymocytes and T lymphocytes.
- Isotype:
- Mouse IgG2b
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
