Anti-CD89 Monoclonal Antibody (Clone:A59)-PE Conjugated
Product Sizes
100 tests
£620.00
30-2119-100TESTS
About this Product
- SKU:
- 30-2119
- Additional Names:
- FCAR; CD89; IgA Fc receptor
- translate.label.attr.clone:
- A59
- Clonality:
- Monoclonal
- Conjugate:
- PE
- Extra Details:
- CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble CD89 is detectable in serum and retains its IgA binding capacity. For signal transduction the association with FcR gamma chain homodimers is needed. CD89 is expressed on granulocytes; monocytes; macrophages; dendritic cells and myeloid cell lines. Its expression is upregulated in presence of IgA immune complexes; stimulators (such as LPS; PMA); TNF alpha; IL1 beta or GM-CSF; and it is downregulated in presence of TGF beta and suramin. Binding of IgA-opsonized targets to CD89 leads to phagocytic and cytotoxic processes of the immunologic defense.
- Host:
- Mouse
- Immunogen:
- Ag8.653 myeloma cells
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
