Anti-CD11b / Mac-1 alpha Monoclonal Antibody (Clone:MEM-174)-FITC Conjugated
Product Sizes
100 tests
£581.00
30-1941-100TESTS
About this Product
- SKU:
- 30-1941
- Additional Names:
- ITGAM||CD11B||CR3A
- translate.label.attr.clone:
- MEM-174
- Clonality:
- Monoclonal
- Conjugate:
- FITC
- Extra Details:
- CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1; CR3) is highly expressed on NK cells; neutrophils; monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes; macrophages and granulocytes; facilitating their diapedesis; as well as it mediates the uptake of complement coated particles; serving as a receptor for the iC3b fragment of the third complement component.
- Host:
- Mouse
- Immunogen:
- Human granulocytes
- Isotype:
- Mouse IgG2a
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
