Anti-CD148 Monoclonal Antibody (Clone:MEM-CD148/05)-Biotin Conjugated
Product Sizes
0.1 mg
£581.00
30-1912-0.1MG
About this Product
- SKU:
- 30-1912
- Additional Names:
- PTPRJ||DEP1
- translate.label.attr.clone:
- MEM-CD148/05
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Extra Details:
- CD148 (also known as HPTP-eta or DEP-1) is a transmembrane protein tyrosin phosphatase containing eight fibronectin type III extracellular domains. This protein is known to inhibit transduction of mitogenic signals in non-hematopoietic cells (fibroblasts; epithelial cells); and signal transduction downstream of T cell receptor; however; it also augments immunoreceptor signaling in B cells and macrophages via dephosphorylating C-terminal tyrosine of Src-family tyrosine kinases. CD148 expression increases after in vitro activation of peripheral blood leucocytes. It can be also used as marker of the most mature human thymocytes; and leukemic cells corresponding to this stadium of thymocyte differentiation. In contrast; in mice the CD148 expression sharply drops through the double positive stage to the single positive thymocytes.
- Host:
- Mouse
- Immunogen:
- Human recombinant CD148 (amino acids 1-444)
- Isotype:
- Mouse IgG2b
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
