Anti-CD33 Monoclonal Antibody (Clone:HIM3-4)-Biotin Conjugated
Product Sizes
0.1 mg
£581.00
30-1877-0.1MG
About this Product
- SKU:
- 30-1877
- Additional Names:
- CD33||SIGLEC3
- translate.label.attr.clone:
- HIM3-4
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Extra Details:
- CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage; binds sialic acid residues in N- and O-glycans on cell surfaces; and is a therapeutic target for acute myeloid leukemia.
- Host:
- Mouse
- Immunogen:
- NFMY-9s human cell line
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
