Anti-CD71 / Transferrin Receptor Monoclonal Antibody (Clone:MEM-75)-Biotin Conjugated
Product Sizes
0.1 mg
£581.00
30-1854-0.1MG
About this Product
- SKU:
- 30-1854
- Additional Names:
- TFRC
- translate.label.attr.clone:
- MEM-75
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Extra Details:
- CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions); CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions; whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface; where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
- Host:
- Mouse
- Immunogen:
- NALM-6 human pre-B cell line
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
