Anti-CD2 / LFA-2 Monoclonal Antibody (Clone:MEM-65)-Biotin Conjugated
Product Sizes
0.1 mg
£581.00
30-1832-0.1MG
About this Product
- SKU:
- 30-1832
- Additional Names:
- T-cell surface antigen CD2; Erythrocyte receptor; T-cell surface antigen T11/Leu-5
- translate.label.attr.clone:
- MEM-65
- Clonality:
- Monoclonal
- Conjugate:
- Biotin
- Extra Details:
- CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover; T cell activation induces increased CD2 expression and its lateral mobility; making easier contact between CD2 and CD58. Subsequently; T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact; thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.
- Host:
- Mouse
- Immunogen:
- Human peripheral T cells.
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
