Anti-CD169 / Siglec-1 Monoclonal Antibody (Clone:7-239)-APC Conjugated
Product Sizes
100 tests
£620.00
30-1824-100TESTS
About this Product
- SKU:
- 30-1824
- Additional Names:
- SIGLEC1||SN
- translate.label.attr.clone:
- 7-239
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD169; also known as Siglec-1 or sialoadhesin; is a type I transmembrane glycoprotein of the sialic acid binding Ig-like lectin family. It binds to sialylated glycoproteins on various haematopoietic cells to mediate cell-cell interactions. CD169 is expressed on a subset of macrophages and dendritic cells. On CD14+ monocytes its expression can be induced by interferon alpha and gamma. High expression of CD169 is observed in the spleen; lymph nodes; bone marrow; and under inflammatory conditions rheumatoid arthritis and atherosclerosis; lower in the liver; lungs and gut. It has been shown to be involved in antigen presentation to invariant NKT cells; which play an important role in the innate arm of the immune system to modulate the subsequent acquired immune responses.
- Host:
- Mouse
- Immunogen:
- human rhinovirus 14-infected monocyte-derived dendritic cells
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
