Anti-CD42a Monoclonal Antibody (Clone:GR-P)-APC Conjugated
Product Sizes
100 tests
£620.00
30-1816-100TESTS
About this Product
- SKU:
- 30-1816
- Additional Names:
- GP9
- translate.label.attr.clone:
- GR-P
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD42a; also known as Glycoprotein 9 (GPIX); composes together with GPIb alpha; GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury; as well as to thrombin; coagulation factors XI and XII; high molecular wight kininogen; TSP-1; integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome; also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
- Host:
- Mouse
- Immunogen:
- Human acute lymphoblastic leukemia cells
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
