Anti-CD83 Monoclonal Antibody (Clone:HB15e)-APC Conjugated
Product Sizes
100 tests
£620.00
30-1799-100TESTS
About this Product
- SKU:
- 30-1799
- Additional Names:
- CD83
- translate.label.attr.clone:
- HB15e
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD83 is a 40-45 kDa heavily glycosylated type I cell surface glycoprotein of immunoglobulin family. It is expressed on the surface of mature dendritic cells; Langerhans cells in the skin; and interdigitating reticulum cells in the lymphoid tissues. Low expression of CD83 has been reported in activated T and B cells. Cytoplasmic expression of CD83 can be detected also in monocytes and macrophages. CD83 is involved in modulation of antigen presentation. Soluble CD83 has immunoregulatory functions; it is able to down-regulate dendritic cell maturation and stimulation of T cells. In the developing immune system; release of soluble CD83 from dendritic cells upon stimulation by gram-positive or gram-negative bacteria has anti-allergic effect. Herpes simplex virus; on the other hand; causes CD83 degradation in mature dendritic cells.
- Host:
- Mouse
- Immunogen:
- Human CD83-transfected Cos cells
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
