APC Conjugated; Anti-CD103 / Integrin alpha E Monoclonal Antibody (Clone:Ber-ACT8)
Product Sizes
100 tests
£620.00
30-1793-100TESTS
About this Product
- SKU:
- 30-1793
- Additional Names:
- ITGAE
- translate.label.attr.clone:
- Ber-ACT8
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD103 / Integrin alphaE is an integrin subunit that is expressed on intraepithelial lymphocytes; epithelial dendritic cells; lamina propria-derived dendritic cells; a subpopulation of lamina propria T cells; a small subset of peripheral lymphocytes; namely T reg cells; and on activated and TGF-beta stimulated lymphocytes. CD103 is in mature form cleaved into two disulfide-linked chains (C-terminal 150 kDa chain and N-terminal 25 kDa chain). It heterodimerizes with integrin beta7 subunit to form alphaE/beta7 integrin (mucosal lymphocyte 1 antigen); which through binding E-cadherin mediates homing of lymphocytes to the intestinal epithelium; and; in addition to the role in adhesion; may serve as an accessory molecule for intraepithelial lymphocyte activation.
- Host:
- Mouse
- Immunogen:
- HTLV-1 induced human T cell line MAPS16
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
