APC Conjugated; Anti-CD64 / FcgammaRI Monoclonal Antibody (Clone:10.1)
Product Sizes
100 tests
£620.00
30-1776-100TESTS
About this Product
- SKU:
- 30-1776
- Additional Names:
- FCGR1A||FCG1||FCGR1||IGFR1
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD64 (FcgammaRI) is a cell surface receptor for Fc region of IgG. It is composed of specific ligand binding alpha subunit and promiscuous gamma subunit; which is indispensable for tyrosine-based signaling. However; even the alpha subunit can transduce signals leading to cellular effector functions. The isoform FcgammaRIa1 binds human IgG with high affinity; has limited myeloid cell distribution; and a relatively large intracellular domain. Products of related genes include FcgammaRIb and FcgammaRIc isoforms; but these specify low affinity IgG receptors if functionally expressed at all. Besides a role in antigen clearance; FcgammaRI (a1) can potently enhance MHC class I and II antigen presentation in vitro and in vivo.
- Host:
- Mouse
- Immunogen:
- Rheumatoid synovial fluid cells and fibronectin purified human monocytes
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
