Anti-CD180 Monoclonal Antibody (Clone:G28-8)-APC Conjugated
Product Sizes
100 tests
£620.00
30-1772-100TESTS
About this Product
- SKU:
- 30-1772
- Additional Names:
- CD180||LY64||RP105
- translate.label.attr.clone:
- G28-8
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD180; also known as RP105 (or Bgp95; LY64) is a type I membrane glycoprotein of Toll-like receptor (TLR) family. Its cytoplasmic tail is short and unlike the TLRs; it lacks the TIR domain. CD180 expression is dependent on the coexpression of its helper molecule; MD-1 ; and mirrors that of TLR4 on antigen-presenting cells. CD180 regulates recognition of LPS and signaling in B cells; via interacting directly with the TLR4 signaling complex; inhibiting its ability to bind microbial ligands. Ligation of CD180 by monoclonal antibodies leads to B cell activation; upregulation of CD80/CD86; and increase in cell size.
- Host:
- Mouse
- Immunogen:
- Human tonsillar B cells
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
