Anti-CD158d / KIR2DL4 Monoclonal Antibody (Clone:mAb#33)-APC Conjugated
Product Sizes
100 tests
£620.00
30-1767-100TESTS
About this Product
- SKU:
- 30-1767
- Additional Names:
- KIR2DL4||CD158D||KIR103AS
- translate.label.attr.clone:
- mAb#33
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD158d / KIR2DL4 is a KIR family member that shares structural features with both activating and inhibitory receptors and may mediate different functions under different circumstances. It contains cytoplasmic ITIM; suggesting inhibitory function; but also transmembrane domain similar to those of activating KIRs. It has been reported that CD158d serves as an inhibitory receptor for peripheral and uterine NK cells; but its ligation with soluble mAbs (unlike immobilized mAbs) results in activation of IFN-gamma secretion. CD158d also binds both membrane form and soluble form of its ligand HLA-G.
- Host:
- Mouse
- Immunogen:
- NK3.3 cells and KIR2DL4-Ig fusion protein
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
