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Antibodies

Anti-CD140b / PDGF-RB Monoclonal Antibody (Clone:18A2)-APC Conjugated

Product Sizes
100 tests
£620.00
30-1760-100TESTS
About this Product
SKU:
30-1760
Additional Names:
PDGFRB||PDGFR||PDGFR1
translate.label.attr.clone:
18A2
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
CD140b / PDGF-RB (platelet-derived growth factor receptor beta) is a cell surface receptor for members of platelet-derived growth factor family; whose intracellular part contains a tyrosine kinase domain. CD140b forms homodimers; or heterodimerizes with CD140a / PDGF-RA. Whereas CD140a can have both pro-proliferative or anti-proliferative effects; the CD140b induces in various cell types their proliferation and migration. CD140b has also developmental roles in the cardiovascular system and is preferentially expressed on some tumours such as medulloblastoma.
Host:
Mouse
Immunogen:
CD140b-transfected NIH 3T3 cells
Isotype:
Mouse IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 1: Anti-Hu CD140b APC antibody (concentration in sample 5 μg/ml; red-filled histogram) binds specifically to CD140b on surface of PFGF-RB transfected 3T3 cells (upper panel); but not to non-transefected 3T3 cells (lower panel). Level of non-specific binding was assessed using Mouse IgG1 isotype control APC antibody (MOPC-21) under same conditions (concentration in sample 5 μg/ml; black-dashed histogram).