Anti-CD135 Monoclonal Antibody (Clone:BV10A4)-APC Conjugated
Product Sizes
100 tests
£620.00
30-1757-100TESTS
About this Product
- SKU:
- 30-1757
- Additional Names:
- FLT3||CD135||FLK2||STK1
- translate.label.attr.clone:
- BV10A4
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD135 / FLT3; also known as FLK2 or STK-1 is a receptor tyrosine kinase that plays important roles in hematopoiesis. After binding of Flt3 ligand (FL); CD135 homodimerizes and stimulates proliferation; differentiation and protects the cell from apoptosis. The loss of CD90 and gain of CD135 expression marks the loss of self-renewal in hematopoietic stem cell population. Detectable CD135 expression appears first at low levels on the surface of primitive multilineage progenitor cells and disappears during defined stages of B-cell development; but is upregulated and maintained during maturation of monocytes. CD135 is also expressed on thymocytes; dendritic cell progenitors and on mature dendritic cells; as well as on various malignant hematopoietic cells.
- Host:
- Mouse
- Immunogen:
- BV-173 leukemic cell line
- Isotype:
- Mouse IgG1
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
