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Antibodies

APC Conjugated; Anti-CD117 / c-Kit Monoclonal Antibody (Clone:104D2)

Product Sizes
100 tests
£620.00
30-1756-100TESTS
About this Product
SKU:
30-1756
Additional Names:
KIT||SCFR
translate.label.attr.clone:
104D2
Clonality:
Monoclonal
Conjugate:
APC
Extra Details:
CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation; adhesion; chemotaxis; apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand; SCF (stem cell factor); CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells; mast cells and various cancer cells; e.g. acute myeloid leukemia cells.
Host:
Mouse
Immunogen:
MOLM-1 megakaryocytic cells
Isotype:
Mouse IgG1
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody