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Antibodies

Anti-CD154 / CD40L Monoclonal Antibody (Clone:24-31)-Low Endotoxin

Product Sizes
0.1 mg
£532.00
30-1663-0.1MG
About this Product
SKU:
30-1663
Additional Names:
CD40LG||CD40L||TNFSF5||TRAP
translate.label.attr.clone:
24-31
Clonality:
Monoclonal
Extra Details:
CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family; and is expressed primarily on activated CD4+ lymphocytes; but also on mast cells; basophils; eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells; including dendritic cells; macrophages; and B cells; and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
Format:
Low Endotoxin
Host:
Mouse
Immunogen:
human CD154 fusion protein
Isotype:
Mouse IgG1
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
Figure 2: Separation of human CD154 positive cells (red-filled) from CD154 negative cells (black-dashed) in flow cytometry analysis (surface staining) of stimulated (PMA + ionomycin) peripheral blood mononuclear cells stained using anti-human CD154 (24-31) purified antibody GAM APC.
Figure 2: Separation of human CD154 positive cells (red-filled) from CD154 negative cells (black-dashed) in flow cytometry analysis (surface staining) of stimulated (PMA + ionomycin) peripheral blood mononuclear cells stained using anti-human CD154 (24-31) purified antibody GAM APC.