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Antibodies

Anti-CD62P / P-selectin Monoclonal Antibody (Clone:AK4)-Low Endotoxin

Product Sizes
0.1 mg
£532.00
30-1645-0.1MG
About this Product
SKU:
30-1645
Additional Names:
SELP||GMRP||GRMP
translate.label.attr.clone:
AK4
Clonality:
Monoclonal
Extra Details:
CD62P (P-selectin) is an adhesion glycoprotein that is expressed on platelets and endothelial cells upon their activation. Interaction between CD62P and its mucin-like ligand PSGL-1 (P-selectin glycoprotein ligand-1) expressed on the microvilli of most leukocytes supports leukocyte rolling along postkapillary venules at the earliest time of inflammation. Both CD62P and PSGL-1 are extended glycoproteins that form homodimers. CD62P dimerization is probably mediated through interactions of the transmembrane domains and stabilizes leukocyte tethering and rolling; probably by increasing rebinding within a bond cluster.
Format:
Low Endotoxin
Host:
Mouse
Immunogen:
Human platelets
Isotype:
Mouse IgG1
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody