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Antibodies

Anti-CD33 Monoclonal Antibody (Clone:WM53)-Low Endotoxin

Product Sizes
0.1 mg
£532.00
30-1644-0.1MG
About this Product
SKU:
30-1644
Additional Names:
CD33||SIGLEC3
translate.label.attr.clone:
WM53
Clonality:
Monoclonal
Extra Details:
CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage; binds sialic acid residues in N- and O-glycans on cell surfaces; and is a therapeutic target for acute myeloid leukemia.
Format:
Low Endotoxin
Host:
Mouse
Immunogen:
Human AML cells
Isotype:
Mouse IgG1
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody