Anti-CD137 / 4-1BB Monoclonal Antibody (Clone:4B4-1)-Low Endotoxin
Product Sizes
0.1 mg
£532.00
30-1586-0.1MG
About this Product
- SKU:
- 30-1586
- Additional Names:
- TNFRSF9||CD137||ILA
- translate.label.attr.clone:
- 4B4-1
- Clonality:
- Monoclonal
- Extra Details:
- CD137; also known as TNFRSF9 or 4-1BB; is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand; known as 4-1BBL; is expressed on activated macrophages; mature B cells; hematopoietic stem cells; and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells; and clonal expansion of T cells; but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.
- Format:
- Low Endotoxin
- Host:
- Mouse
- Immunogen:
- Recombinant human CD137 ectodomain
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
