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Antibodies

Anti-TPX2 Monoclonal Antibody (Clone:TPX2-01)

Product Sizes
0.1 mg
£570.00
30-1585-0.1MG
About this Product
SKU:
30-1585
Additional Names:
TPX2||C20orf1||C20orf2||DIL2||HCA519
translate.label.attr.clone:
TPX2-01
Clonality:
Monoclonal
Extra Details:
TPX2 is a microtubule-associated protein; which is a critical regulator of mitosis. At the beginning of mitosis; TPX2 is released and plays a significant role in mitotic spindle formation and subsequent proper segregation of chromosomes during cell division. After completion of mitosis the TPX2 protein disappears; but has also role in DNA damage response. Its overexpression has been demonstrated in many types of carcinomas. TPX2 belongs to the markers of worse tumor prognosis. On the other hand; down-regulation of TPX2 can inhibit cancer cell proliferation; migration and invasion.
Format:
Purified
Host:
Mouse
Immunogen:
Human TPX2
Isotype:
Mouse IgG1
Purification:
Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Reactivities:
Human, Mouse, Rat
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Immunoprecipitation of TPX2 from nuclear extract of HEK293 cells using monoclonal antibody TPX2-01. 1) nuclear extract; 2) antibody; 3) immunoprecipitate; 4) carrier
Figure 3: Immunocytochemistry of TPX2 using monoclonal antibody TPX2-01 in glioblastoma cell line T98G: a) interphase; b) mitosis. c) Immunohistochemistry of TPX2 in U87MG human glioblastoma cells (orthotopic xenograft in murine brain). Bar: 20 µm.
Figure 3: Immunocytochemistry of TPX2 using monoclonal antibody TPX2-01 in glioblastoma cell line T98G: a) interphase; b) mitosis. c) Immunohistochemistry of TPX2 in U87MG human glioblastoma cells (orthotopic xenograft in murine brain). Bar: 20 µm.