Anti-CD111 / Nectin-1 Monoclonal Antibody (Clone:R1.302)
Product Sizes
0.1 mg
£532.00
30-1563-0.1MG
About this Product
- SKU:
- 30-1563
- Additional Names:
- NECTIN1||HVEC||PRR1||PVRL1
- translate.label.attr.clone:
- R1.302
- Clonality:
- Monoclonal
- Extra Details:
- CD111; also known as nectin-1; is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells. It also serves as a target molecule for entry of herpes simplex virus (HSV-1; HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells. CD111 is connected with actin cytoskeleton through afadin. Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- NIH/3T3 cells transfected with human CD111
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
