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Antibodies

Anti-CD112 / Nectin-2 Monoclonal Antibody (Clone:R2.525)

Product Sizes
0.1 mg
£532.00
30-1561-0.1MG
About this Product
SKU:
30-1561
Additional Names:
NECTIN2||HVEB||PRR2||PVRL2
translate.label.attr.clone:
R2.525
Clonality:
Monoclonal
Extra Details:
CD112; also known as nectin-2; is a transmembrane glycoprotein involved in organization of adherens junctions. It also serves as a target molecule for entry of certain strains of herpes simplex virus (HSV) and pseudorabies virus (PRV). It is homologous to CD155; which serves as a target molecule for polio virus. CD112 seems to play a role in neural tube formation; with N-cadherin. Inside the cell; CD112 is connected with actin cytoskeleton through afadin. Variations in the CD112 gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
Format:
Purified
Host:
Mouse
Isotype:
Mouse IgG1
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody