Anti-CD158a/g/h Monoclonal Antibody (Clone:HP-MA4)
Product Sizes
0.1 mg
£532.00
30-1560-0.1MG
About this Product
- SKU:
- 30-1560
- Additional Names:
- KIR2DL1||CD158A||NKAT1
- translate.label.attr.clone:
- HP-MA4
- Clonality:
- Monoclonal
- Extra Details:
- Killer cell immunoglobulin-like receptors (KIRs) are polymorphic transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. They are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain (such as CD158a / KIR2DL1) transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM); while KIR proteins with the short cytoplasmic domain (such as CD158g / KIR2DS5; CD158h / KIR2DS1; or KIR2DS3) lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for CD158 isoforms are subsets of MHC class I molecules.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- Human NK cell line LB2
- Isotype:
- Mouse IgG2b
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
