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Antibodies

Anti-Helios Monoclonal Antibody (Clone:22F6)

Product Sizes
0.1 mg
£570.00
30-1557-0.1MG
About this Product
SKU:
30-1557
Additional Names:
IKZF2||HELIOS||ZNFN1A2
translate.label.attr.clone:
22F6
Clonality:
Monoclonal
Extra Details:
Helios; also known as IKZF2 (Ikaros family zinc finger protein 2) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development; together with other members of this family; such as Aiolos and Ikaros. Helios forms homo- and heterodimers with these proteins and is thought to function predominantly in early hematopoietic development. Expression of Helios; Aiolos and Ikaros is restricted to cells of the hematopoietic system; whereas other family members; Eos and Pegassus; are more widely expressed. Helios is expressed at early stages of thymocyte development. In mature T cells; Helios has been strongly associated with Treg cells.
Format:
Purified
Host:
Hamster
Immunogen:
Peptide coresponding to the amino acids 51-107 of Helios
Isotype:
Hamster IgG
Purification:
Purified by protein-A affinity chromatography
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Store at 2-8[o]C. Do not freeze.
Supplier:
Abeomics
Type:
Antibodies:Monoclonal Antibody
  • Manufacturer's Data Sheet:1.jpg
Figure 2: Flow cytometry multicolor surface staining pattern of human lymphocytes stained using anti-human CD3 (UCHT1) PE-Cy7 antibody (4 μl reagent / 100 μl of peripheral whole blood) and intracellular staining pattern using anti-Helios (22F6) purified antibody (concentration in sample 8 μg/ml; GAM APC).
Figure 3: Flow cytometry multicolor surface staining pattern of human T cells stained using anti-human CD4 (MEM-241) Pacific Blue antibody (4 μl reagent / 100 μl of peripheral whole blood) and intracellular staining pattern using anti-Helios (22F6) purified antibody (concentration in sample 8 μg/ml; GAM APC).
Figure 4: Separation of human CD4 positive Helios positive T cells (red-filled) from CD4 negative Helios negative lymphocytes (black-dashed) in flow cytometry analysis (intracellular staining) of human peripheral whole blood stained using anti-Helios (22F6) purified antibody (concentration in sample 8 μg/ml; GAM APC).
Figure 4: Separation of human CD4 positive Helios positive T cells (red-filled) from CD4 negative Helios negative lymphocytes (black-dashed) in flow cytometry analysis (intracellular staining) of human peripheral whole blood stained using anti-Helios (22F6) purified antibody (concentration in sample 8 μg/ml; GAM APC).