Anti-DR3 / TRAMP Monoclonal Antibody (Clone:JD3)
Product Sizes
0.1 mg
£532.00
30-1547-0.1MG
About this Product
- SKU:
- 30-1547
- Additional Names:
- TNFRSF25||APO3||DDR3||DR3||TNFRSF12||WSL||WSL1||UNQ455/PRO779
- translate.label.attr.clone:
- JD3
- Clonality:
- Monoclonal
- Extra Details:
- DR3; also known as APO-3; TRAMP or TNFRSF12; is a death domain-containing receptor of TNFR family; which is expressed preferentially in peripheral blood leukocytes and in the lymphocyte-enriched tissues. Its expression has been shown to be especially up-regulated in activated T cells. DR3 participates e.g. in the removal of self-reactive T cells in the thymus. The ligand for DR3 is TL1A (TNF-like ligand 1A); which is expressed in a variety of cell types (induced by inflammatory stimuli); and can also be released as a soluble factor. The TL1A/DR3 axis has been shown to costimulate T cells to produce a wide variety of cytokines and leads to T cell differentiation towards Th1 and Th17 types.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- human DR3-Ig fusion protein
- Isotype:
- Mouse IgG1
- Purification:
- Purified by protein-A affinity chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
