APC Conjugated Anti-Human CD266 Monoclonal Antibody (Clone: ITEM-4)
Product Sizes
0.1 mg
£620.00
30-1545AC-0.1MG
About this Product
- SKU:
- 30-1545AC
- Additional Names:
- TNF receptor superfamily member 12A; TWEAKR; FN14; TNFRSF12A
- translate.label.attr.clone:
- ITEM-4
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD266 / TWEAK R (TNFRSF12A); also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK; the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells; as well as on some cancer tissues; and plays a role in CD255-induced endothelial cell migration; proliferation; and angiogenesis. The CD255-CD266 interaction; or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells); which might have therapeutic potential. Specificity: The mouse monoclonal antibody ITEM-4 recognizes an extracellular epitope of CD266 / TWEAK R; a TNFR superfamily receptor for CD255 / TWEAK; a TNF-like weak inducer of apoptosis.
- Host:
- Mouse
- Immunogen:
- Human CD266-transfected P815 cells
- Isotype:
- Mouse IgG2b
- Purification:
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human, Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Protect from prolonged exposure to light. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:1.jpg
