Anti-CD95 / Fas Monoclonal Antibody (Clone:EOS9.1)
Product Sizes
0.1 mg
£532.00
30-1543-0.1MG
About this Product
- SKU:
- 30-1543
- Additional Names:
- Apo-1 antigen; Apoptosis-mediating surface antigen FAS;
- translate.label.attr.clone:
- EOS9.1
- Clonality:
- Monoclonal
- Extra Details:
- CD95 (Fas; APO-1); a 46 kDa transmembrane glycoprotein; is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains; formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC; in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis; Fas also triggers pro-inflammatory cytokine responses.
- Format:
- Purified
- Host:
- Mouse
- Immunogen:
- P815 cells transfected with human CD95
- Isotype:
- Mouse IgM
- Purification:
- Purified by precipitation and chromatography
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store at 2-8[o]C. Do not freeze.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:download_pdf.php
