APC Conjugated Anti-CD88 / C5aR Monoclonal Antibody (Clone:S5/1)
Product Sizes
100 tests
£649.00
30-1531AC-100TESTS
About this Product
- SKU:
- 30-1531AC
- Additional Names:
- C5AR1||C5AR||C5R1
- translate.label.attr.clone:
- S5/1
- Clonality:
- Monoclonal
- Conjugate:
- APC
- Extra Details:
- CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade; and is expressed mainly by monocytes; macrophages; neutrophils; eosinophils; and mast cells; but also e.g. by hepatocytes; glial cells; vascular endothelial cells; or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response; including superoxide anion production; chemotaxis; and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.
- Host:
- Mouse
- Immunogen:
- Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR
- Isotype:
- Mouse IgG2a
- Purification:
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store in the dark at 2-8[o]C. Do not freeze. Avoid prolonged exposure to light.
- Supplier:
- Abeomics
- Type:
- Antibodies:Monoclonal Antibody
- Manufacturer's Data Sheet:30-1531AC 1.jpeg
